Fig. 5.
Fig. 5. T-cell proliferation in response to CLL cells infected with hf-HSVCD40L compared with cells transduced with HSVCD40L. / CLL were left untreated (mock infected) or were transduced with equivalent transduction units of HSVlac, hf-HSVlac, HSVCD40L, or hf-HSVCD40L. Cells were then metabolically labeled with [3H]-thymidine in a standard mLTR reaction. [3H]-thymidine uptake data are expressed as counts per minute (cpm). Error bars represent standard deviation. Asterisk indicates statistical significance (Pā€‰<ā€‰.001) as determined by single-factor analysis of variance. Data are representative of 4 different patient samples.

T-cell proliferation in response to CLL cells infected with hf-HSVCD40L compared with cells transduced with HSVCD40L.

CLL were left untreated (mock infected) or were transduced with equivalent transduction units of HSVlac, hf-HSVlac, HSVCD40L, or hf-HSVCD40L. Cells were then metabolically labeled with [3H]-thymidine in a standard mLTR reaction. [3H]-thymidine uptake data are expressed as counts per minute (cpm). Error bars represent standard deviation. Asterisk indicates statistical significance (Pā€‰<ā€‰.001) as determined by single-factor analysis of variance. Data are representative of 4 different patient samples.

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