Caspase-3 activation induced by UV light, cytochrome

c, and granzyme B. (A) UV light–induced caspase-3 activation. S-100 was extracted from cells after exposure to UV light for 3 hours. (B) Cytochrome c–induced casapase-3 activation. S-100 from the 3 cell lines was incubated with cytochromec and dATP for 1 hour. (C) Granzyme B–induced caspase-3 activation. S-100 from the 3 cell lines was incubated with 2 U granzyme B for 1 hour.