Fig. 5.
Intravenous injection of MV slows progression of Raji tumors.
Prominent perivascular anti–MV H staining is observed in tumor sections after systemic injection of MV. (A) Mice bearing established Raji xenografts were injected intravenously with 107 pfu MV on 4 occasions (days 0, 3, 5, and 7) (●) or UV-inactivated control virus (♦). The x-axis represents time after MV injection. The y-axis represents tumor volume (cm3). (B) A section of Raji tumor after intravenous injection of MV. Immunoreactivity with anti–MV H antibody appears as orange-brown staining around a blood vessel.