American Society of Hematology

Fig. 6.

$Fig. 6. Leukocyte rolling velocities in TNFα-treated mice. / Cumulative velocity distribution for core 2−/− mice (solid line) and control mice (dotted line) with no treatment (A), P-selectin–blocking mAb RB40.34 and L-selectin–blocking mAb MEL14 (B), and E-selectin–blocking mAb 9A9 (C). Significant velocity differences (P < .05) between control and core 2−/− mice were detected when E-selectin was blocked (C). Rolling flux fraction for controls was 21%, 13%, and 58% for panels A, B, and C, respectively, and for core 2−/− mice, 8%, 2%, and 3%.$

Leukocyte rolling velocities in TNFα-treated mice.

Cumulative velocity distribution for core 2^−/− mice (solid line) and control mice (dotted line) with no treatment (A), P-selectin–blocking mAb RB40.34 and L-selectin–blocking mAb MEL14 (B), and E-selectin–blocking mAb 9A9 (C). Significant velocity differences (P < .05) between control and core 2^−/− mice were detected when E-selectin was blocked (C). Rolling flux fraction for controls was 21%, 13%, and 58% for panels A, B, and C, respectively, and for core 2^−/− mice, 8%, 2%, and 3%.

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