Fig. 4.
![Fig. 4. Functional responses after IL-12 stimulation of cytokine-primed T cells. / Activated T cells were primed with or without cytokines as indicated for 2 days. These cells were then washed and treated with or without IL-12 for 2 days. IFN-γ produced by activated cells was quantified by ELISA (A). All values represent net IFN-γ production measured by the difference between levels produced in the presence and absence of IL-12. T-cell proliferation (B) was quantified by measuring the incorporation of [3H]TdR. The fold proliferation compares values in T cells treated with IL-12 versus T cells without additional IL-12.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/97/12/10.1182_blood.v97.12.3860/6/h81211192004.jpeg?Expires=1735525697&Signature=jM6bDE0mhP7XqZpYt43sHGTz6Pg7IlwZh3TPVlaQii3a4hmDmlY4Nu3DvDvfhB96wIqfOFf-Nb6Bd0OFD---LpDjs3eIalUx~-vL~WGNZsyH2akyJSKoKW8jPcgBzFa-~R7Jtksn68wA9Jc2SBOIiALmb1yhU6Z2mPmmUmLXUvh4GQ8DBM4hcj2e8iANlSaeQIknSABCJrr6UeRTE1vVFQyETx3sw8cV4YGENNA-KWjwwHdMCIN0yLnmNXZEAs9uJU6DwHthc-qm3exDlAMxTXlTeAp1qg1qvvb9CTmfLCVcdpHOOsRY88uRZY5nsU9o6oT5zltGN~dSWla6nibY6Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Functional responses after IL-12 stimulation of cytokine-primed T cells.
Activated T cells were primed with or without cytokines as indicated for 2 days. These cells were then washed and treated with or without IL-12 for 2 days. IFN-γ produced by activated cells was quantified by ELISA (A). All values represent net IFN-γ production measured by the difference between levels produced in the presence and absence of IL-12. T-cell proliferation (B) was quantified by measuring the incorporation of [3H]TdR. The fold proliferation compares values in T cells treated with IL-12 versus T cells without additional IL-12.
