Fig. 1.
Phagocyte accumulation on the surfaces of PET disks.
Disks were preincubated with human fibrinogen (200 μg/mL), P1-albumin (200 μg/mL), P2-albumin (200 μg/mL), scrambled P1 peptide–albumin (200 μg/mL), scrambled P2 peptide–albumin (200 μg/mL), and albumin (200 000 μg/L [200 μg/mL]) and implanted in Swiss Webster mice for 16 hours. Vertical lines denote ± 1 SD (n = 5 in all cases). (**Significance vs fibrinogen-coated implants is P < .01.) Estimated numbers of Mφs (cells per square centimeter): 425 000 ± 45 000 on fibrinogen-coated disks; 278 000 ± 85 000 on P1-albumin–coated disks; 305 000 ± 115 000 on P2-albumin–coated disks; 17 300 ± 7300 on scrambled P1 peptide-albumin–coated disks; 29 100 ± 8000 on scrambled P2 peptide-albumin–coated disks; and 13 600 ± 11 800 on albumin-coated disks. Estimated numbers of PMNs (cells per square centimeter): 145 700 ± 43 900 on fibrinogen-coated disks; 146 500 ± 73 000 on P1-albumin–coated disks; 131 700 ± 21 300 on P2-albumin–coated disks; 33 900 ± 9100 on scrambled P1 peptide-albumin–coated disks; 25 700 ± 11 300 on scrambled P2 peptide-albumin–coated disks; and 22 200 ± 13 500 on albumin-coated disks.