Fig. 5.
Competition between phages and rGPIbα fragment for binding to respective anti-GPIb mAbs.
(A) Competition between the rGPIbα fragment (serial dilution) and phages for binding to the respective mAbs. (B) Competition between the different 6B4 binding phages (selected from the C7 and the L15 libraries) and the rGPIbα fragment for binding to mAb 6B4. In all instances, the rGPIbα fragment was able to compete with the phages for binding to the mAb, with the exception of phage 2 selected on mAb 12G1 in panel A and the nonsense phage in panel B.