Effect of DFO and 311 concentration on cyclin-dependent kinase inhibitors and other cell-cycle inhibitory molecules.

The SK-N-MC neuroepithelioma cell line or SH-SY-5Y neuroblastoma cell line* was incubated for 30 hours at 37°C with DFO (5-150 μM) or 311 (1-25 μM). Western blot analysis was then performed, as described in “Materials and methods.” Results shown are representative of 3 to 5 separate experiments performed.