Blocking of CHX-induced apoptosis by TECK or SDF-1.

(A) MOLT4 cells were treated as described in Figure 5. Apoptotic cells were measured by annexin-V staining. (B) Ability of TECK to block CHX-induced apoptosis at varied concentrations of CHX. MOLT4 cells were induced to undergo apoptosis by CHX (●) in the presence of TECK (○) or Z-VAD-FMK (▴). Data are expressed as the mean with SD obtained from at least 3 different experiments. (C and D) Dose-dependent effect of TECK or SDF-1 on CHX-induced apoptosis. Data presented are from at least 3 different experiments.