CD40 cross-linking of leukemia cells induces the expression of mRNA for the chemokines MDC and TARC.

CD19⁺ leukemia cells were sorted using a high-speed sorter to obtain near 100% purity. Three representative patients, of 18 tested, are shown. Tumor cells were cultured in AIM V medium in the presence or absence of sCD40L, for 3 days.