Fig. 5.
Fibrinogen Longmont polymerization is impaired.
Fibrin polymerization reaction was initiated by adding 0.05 NIH U/mL thrombin to 0.4 mg/mL normal fibrinogen (solid lines) or fibrinogen Longmont (dashed lines) in the absence of calcium (A) or in the presence of 10 mM calcium (B). (C) The fibrin polymerization curve of the Fr II (monomeric fraction) of normal fibrinogen and fibrinogen Longmont. Each curve is an average of 3 experiments.