Fig. 1.
Characterization of the human and mouse
PBP/PF4 gene locus and transgenic constructs. (A) A dot-matrix comparison of the 2 gene loci calculated at 20 bp with 14-bp match. The exons/introns are shown in gray and the arrows indicating the 5′→3′ transcription orientation. (B) A stick figure of the human PBP/PF4 gene locus in humans is shown at the top with a partial restriction map. The constructs used in these studies including the nomenclature are shown. Their copy number per haploid genome is also indicated. H indicatesHindIII; S, SalI; E, EcoRI. The arrow indicates the direction of transcription.