Fig. 2.
Fig. 2. Dose-response study of the negative regulatory activity of CD4+ T cells. / Different numbers of CD4+ T cells isolated from the tolerant CBA mice were injected into naive CBA mice. After adoptive transfer of the CD4+ T cells, the treated mice were challenged with 2 weekly intravenous injections of 4 × 104 BALB/c PBMCs. One week after the second challenge transfusion, serum samples were harvested and assayed for anti–H-2d antibody activities by immunofluorescence flow cytometry. There were 3 mice in each treatment group. Each value represents the mean ± SD.

Dose-response study of the negative regulatory activity of CD4+ T cells.

Different numbers of CD4+ T cells isolated from the tolerant CBA mice were injected into naive CBA mice. After adoptive transfer of the CD4+ T cells, the treated mice were challenged with 2 weekly intravenous injections of 4 × 104 BALB/c PBMCs. One week after the second challenge transfusion, serum samples were harvested and assayed for anti–H-2d antibody activities by immunofluorescence flow cytometry. There were 3 mice in each treatment group. Each value represents the mean ± SD.

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