Fig. 7.
Immunogenicity of PBMCs of BALB/c mice with knockout of IL-12β chain gene.
CBA (○,●) and BL/6 (▵,▴) mice were transfused with PBMCs (2.5 × 104) from the wild-type (Control) or the IL-12β chain knockout (IL-12 KO) BALB/c mice weekly for 2 weeks. The development of antibody to BALB/c leukocytes in the serum collected 1 week after the second transfusion was measured by immunofluorescence flow cytometry. MFIs for preimmune CBA and BL/6 mice were 14 and 9, respectively.
