Schematic representation of the structures of normal GPIIIa (WT) and GPIIIa in IJ-1, C655S, and Stop657 mutants.

Extracellular (EC), transmembrane (TM), and cytoplasmic (CY) domains are depicted. Nucleotide and amino acid sequences are shown. C/S at 655 is circled, and the 11-bp deletion of IJ-1 mutation is boxed.