Fig. 1.
Pseudo Pelger-Huët anomaly forms.
Panels A through E depict the Stodtmeister, or unilobed, form. Early granulocyte with coarse chromatin segregated toward the periphery of the nucleus. (A) PB Giemsa from an MDS patient (magnification × 100). (B) ISEL showing a pseudo Pelger-Huët cell undergoing apoptosis (magnification × 100). (C-E) Electron micrographs showing the classical apoptotic features (uranyl acetate and lead citrate staining; original magnifications, × 6600, × 10 000, and × 6600, respectively). Panels F through J depict the bilobed form. Mature neutrophil showing bilobed nucleus with marked chromatin condensation and altered cytoplasm. (F) PB Giemsa from an MDS patient (magnification × 100). (G) ISEL showing a pseudo Pelger-Huët cell undergoing apoptosis (magnification × 100). (H- J) Electron micrographs showing the classical apoptotic features (uranyl acetate and lead citrate staining; original magnifications, × 8300, × 6600, and × 6600, respectively).