Fig. 3.
Relation between MDM2 levels and p53 dysfunction.
MDM2 levels in 4 CLL patients with type B p53 dysfunction and noTP53 gene defects were compared with those in 4 patients with functionally intact p53 and in 4 patients with type A p53 dysfunction and TP53 mutations. Average mean fluorescence intensity values (± SE) obtained by FACS analysis are shown for each group.