Fig. 7.
Engrafting marrow stem cells at varying times after 1 Gy WBI.
Male BALB/c mice were exposed to 1 Gy WBI and marrow was harvested immediately (time 0) or 6, 12, or 24 weeks later. This marrow was then assayed for engraftment potential in 1 Gy–irradiated female hosts 8 weeks after cell infusion. Data are expressed as a percentage of male cells as determined by FISH. There were 4 to 5 mice per experiment and 5, 4, 2, and 1 experiments at 0, 6, 12, and 24 weeks, respectively. Nonirradiated marrow (40 × 106 cells) infused into 1 Gy–treated hosts gave a mean of 68% ± 8% (5 experiments, 25 mice). Data are expressed as a mean ± 1 SD.
