Amino acid alignment of DUB-1, DUB-2, and DUB-2A proteins.

The predicted amino acid sequences of DUB-1, DUB-2, and DUB-2A are shown. Boxed residues are different among the various DUB proteins. The hypervariable region of the DUB-2A protein extends from amino acids 432 through 451. On the basis of this alignment, DUB-2A has a 95% identity with DUB-2 and an 86% identity with DUB-1.