Electron microscopy of hepatocytes from

Fancc^−/−Sod1^−/− mice reveals no increase in organelle damage. Hepatocytes fromFancc^+/−Sod1^+/−(A,C) andFancc^−/−Sod1^−/−(B,D) mice stained with osmium tetroxide. (A) A normal multinucleated centrilobular hepatocyte (× 5400) and (C) a higher magnification showing normal organelles (× 11 750). (B) Microvesicular steatosis in a centrilobular Fancc^−/−Sod1^−/−hepatocyte (× 5400) and (D) (× 11 750).