Alignment of the proteins encoded by the zebrafish and human MPO genes.

Sequence comparison was performed using the FASTA program in the Genetics Computer Group (GCG) software. Identical amino acids are denoted by bars and similar amino acids by double dots. The human and zebrafish proteins share 76.5% similarity and 49.6% identity at the amino acid level. In the MPO catalytic domain (underlined), the 2 sequences share 82.8% similarity and 56.8% identity.