Fig. 4.
Effect of thrombin, TNF-α, and IL-1β on thrombus formation on HMEC-1 and HUVEC compared with VT-1.
Endothelial cells were incubated with thrombin (2 U/mL, 10 minutes), TNF-α (100 U/mL, 4 hours), IL-1β (100 U/mL, 4 hours), or VT-1 (10 pM, 24 hours), perfused with blood at 60 dynes/cm2, and examined under confocal microscopy. Data are expressed as mean ± SE of percent of area covered by thrombi in respect to VT-1 (100%) (n = 3 experiments). *P < .01 versus VT-1.
