Fig. 6.
Fig. 6. Effect of blockade of vWF binding to platelet GPIb or αIIbβ3 with specific inhibitors on VT-1–induced thrombus formation on HMEC-1. / ATA (100 μg/mL), which inhibits vWF binding to GPIb, or 7E3 Fab (20 μg/mL), an anti-αIIbβ3, was added to blood 5 minutes before perfusion over HMEC-1. Data are expressed as mean ± SE (n = 6 experiments). °P < .01 versus control; *P < .01 versus VT-1.

Effect of blockade of vWF binding to platelet GPIb or αIIbβ3 with specific inhibitors on VT-1–induced thrombus formation on HMEC-1.

ATA (100 μg/mL), which inhibits vWF binding to GPIb, or 7E3 Fab (20 μg/mL), an anti-αIIbβ3, was added to blood 5 minutes before perfusion over HMEC-1. Data are expressed as mean ± SE (n = 6 experiments). °P < .01 versus control; *P < .01 versus VT-1.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal