Fig. 1.
Anti–Thy-1 inhibits IL-2–induced T-cell proliferation.
The 2.10 T-cell clone (A) or the CTLL-2 T-cell line (B) were cultured in wells precoated with mAbs specific for Thy-1 (○) or an mAb isotype control (●) and the indicated concentration of IL-2. (C) Resting or TcR-stimulated CD8+ lymph node T cells were cultured in wells precoated with anti–Thy-1 or an isotype control in the presence of 15 U/mL IL-2. Uptake of 3H-thymidine was assessed after 20 hours of culture.
