PECAM-1–deficient platelets demonstrate enhanced collagen- and CRP-induced platelet aggregation responses.

PRP from PECAM-1^+/+ and PECAM-1^−/− mice was stimulated with collagen (30 μg/mL) and CRP (10 μg/mL) under stirring conditions, and aggregation was monitored by changes in light transmission. The ordinate represents percentage changes in light transmission. Data are representative of 3 experiments.