The concentration of sVCAM-1 and NE is enhanced in the serum of mobilized patients.

(A) sVCAM-1 concentration in the serum of patients mobilized with either rhuG-CSF alone (●), rhuG-CSF in combination with rhuSCF (▪), or rhuIL-3 in combination with rhuGM-CSF (▴) taken just prior to the commencement of HGF administration and on blood collection day. Each pair of dots represents a different patient. (B) These results are expressed versus the number of mobilized CFUs collected by apheresis on collection day. (C) NE concentration in the serum of patients mobilized with either rhuG-CSF alone, rhuG-CSF in combination with rhuSCF, or rhuIL-3 in combination with rhuGM-CSF taken just before the start of HGF administration and on blood collection day. NE concentrations on collection day are plotted versus the number of CFUs collected in PB (D) or versus the increase of sVCAM-1 plasma concentration (E). Correlations and significances were determined with the nonparametric Spearman correlation statistic.