In vitro LAK cell–mediated cytotoxicity levels of MNCs.

In vitro LAK cell–mediated cytotoxicity levels of MNCs from G-CSF–mobilized (n = 75) or nonmobilized steady-state (n = 28) donor blood stem cell harvests against K562 (panel A) and Raji (panel B) tumor target cells by means of ⁵¹Cr release assay following in vitro activation with IL-2 for 72 hours. Values represent mean percentages of specific cytotoxicity ± SEM from different samples. (For E/T ratios of 12.5:1, P = .005; 25:1,P = .007; 50:1, P = .01; 100:1,P = .05.) ● indicates nonmobilized donors; ▵, G-CSF mobilized donors; *indicates the statistical significance of the value as compared to nonmobilized blood.