In vitro LAK cell–mediated cytotoxicity levels of MNCs.

In vitro LAK cell–mediated cytotoxicity levels of MNCs from 2 different doses (5 μg/kg, n = 35; 10 μg/kg, n = 69) of G-CSF–mobilized donor stem cell harvests against K562 (panel A) and Raji (panel B) tumor target cells by means of ⁵¹Cr release assay following in vitro activation with IL-2 for 72 hours. Values represent mean percentages of specific cytotoxicty + SEM from different samples. (For all E/T ratios for K562, P = .001. For Raji, E/T ratios of 12.5:1 were not significant, while for E/T ratios of 25:1, P = .01; 50:1, P = .01; 100:1, P = .05). ● indicates 5 μg/kg G-CSF; ○, 10 μg/kg G-CSF.