Repopulation of total CD8⁺ T cells after allogeneic, T-cell–depleted SCT.

(A) CMV-seronegative patients (n = 9); (B) CMV-seropositive patients without CMV antigenemia after SCT (n = 4); (C) CMV-seropositive patients developing CMV antigenemia but no CMV disease (n = 10); (D) CMV-seropositive patients developing CMV antigenemia and CMV disease (n = 4). Logarithmic scales were used for the y axes to compress the figure. For each patient group, the median values per time point are connected with a line. In each panel, the upper and lower horizontal lines indicate the 95th and 5th percentiles of 29 healthy CMV-seropositive HLA-A2⁺ individuals, respectively. SCT, stem cell transplantation.