Fig. 3.
Survival days for the groups of mice immunized with HSP70 derived from other syngeneic tumor cell lines.
Ten days after BMT, recipient mice were inoculated with 2.5 × 104 A20 cells (day 0). Mice were immunized with HSPs on day 4, 9, 14, and 19, immunized with PBS (○), 40 μg HSP70 derived from A20 cells (■), 40 μg HSP70 derived from T27A cells (▴), and 40 μg HSP70 derived from colon 26 cells (●). Mice immunized with HSP70 derived from A20, but not HSP70 derived from other syngeneic tumor cells, had significantly enhanced survival. *P < .05 versus PBS, T27A and, colon 26; Wilcoxon test. There were 5 mice in each group. Data are representative of 3 separate experiments.