Fig. 4.
Percentages of HTLV-1–infected CD4+ and CD8+ T cells expressing Tax in 4 HAM/TSP patients.
Percentages were calculated using the proviral load of CD4+and CD8+ isolates and maximum Tax expression observed in each T-cell type. Percentages of infected cells expressing Tax were calculated as follows: (number of CD4+ or CD8+cells expressing Tax/total number of CD4+ or CD8+ cells in PBMC culture)/(proviral load in purified CD4+ or CD8+ T cells). Striped bars represent percentages obtained for CD4+ T cells, and black bars represent proportions obtained for CD8+ T cells.