Fig. 3.
Reactivity of PA autoantibodies with GPIIbD163A-IIIa.
Eluates from patients 1, 3, and 8, with impaired binding to KO variant GPIIb-IIIa, showed the impaired binding to GPIIbD163A-IIIa. Results are expressed as ΔOD: [OD value obtained from a test sample − (mean + 3 SD) OD value obtained from 5 control samples]. Open columns represent ΔOD value in antigen-capture ELISA using WT GPIIb-IIIa, and filled columns represent ΔOD value in antigen-capture ELISA using GPIIbD163A-IIIa.