Fig. 4.
Reactivity of PA autoantibodies with CAM variant GPIIb-IIIa.
(A) Reactivity of mAbs (AP3 and OP-G2) and antiplatelet allo-antibodies (anti–HPA-1a and anti–HPA-3a) with CAM variant GPIIb-IIIa. (B) Reactivity of PA autoantibodies with CAM variant GPIIb-IIIa. Results are expressed as ΔOD: [OD value obtained from a test sample − (mean + 3 SD) OD value obtained from 5 control samples]. Open columns represent ΔOD value in antigen-capture ELISA using WT GPIIb-IIIa, and filled columns represent ΔOD value in antigen-capture ELISA using CAM variant.