Fig. 5.
Fig. 5. Calcium signaling inhibits IL-12 production by DCs. / DCs were activated with IFN-γ, TNF-α, and CD40L in the presence of the indicated concentrations of CI, and IL-12 p70 production was measured by ELISA. Levels of p70 IL-12 production by DCs activated with IFN-γ, TNF-α, and CD40L were 2000 to 3000 pg/mL. Results are based on triplicate cultures from a single representative experiment with SEM. Three other experiments demonstrated similar results.

Calcium signaling inhibits IL-12 production by DCs.

DCs were activated with IFN-γ, TNF-α, and CD40L in the presence of the indicated concentrations of CI, and IL-12 p70 production was measured by ELISA. Levels of p70 IL-12 production by DCs activated with IFN-γ, TNF-α, and CD40L were 2000 to 3000 pg/mL. Results are based on triplicate cultures from a single representative experiment with SEM. Three other experiments demonstrated similar results.

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