CD3⁺/CD25⁺-to-CD3⁺/HLA-DR⁺ratios and selective reduction in CD4⁺/CD25⁺ T cells.

(A) Boxplots depict the 10th, 25th, 50th (median), 75th, and 90th percentiles of the CD3⁺/CD25⁺-to-CD3⁺/HLA-DR⁺ratios. Ratios were obtained by dividing the absolute number of CD3⁺/CD25⁺ T cells by the absolute number of CD3⁺/HLA-DR⁺ T cells. Bold numbers in or next to the boxes denote median values of the ratios in each group. The ratios of the groups were compared by Mann-Whitney U test. NS indicates not significant. (B) Boxplots depict the 10th, 25th, 50th (median), 75th, and 90th percentiles of CD25⁺CD4⁺ T cells in 26 individuals of the proband Ia, 17 subjects from M+/A+, and the HC groups. The groups were compared by Mann-Whitney U test. NS indicates not significant.