Engraftment kinetics of adult mouse BM, FL, and MPB cells containing equal numbers of hematopoietic progenitors.
Lethally irradiated Ly-5.1 mice were injected with 1.2 × 106 Ly-5 congenic day 14 FL cells (●; n = 20 mice from 2 experiments) or 6.7 × 106cyclophosphamide/G-CSF MPB cells (■; n = 28 mice from 3 experiments), each containing the same number of CFCs as 2 × 106 BM cells (dashed line; reproduced from Figure1). Shown are the mean ± SEM number of peripheral blood leukocytes (A), erythrocytes (B), and platelets (C) counted on the indicated days after transplantation. The vertical bars along the y-axis define the ranges of blood counts in normal Ly-5.1 mice. SEs not shown are too small for the scale used. Note that the time after transplantation is not depicted on a linear scale.
