Fig. 7.
Fig. 7. Red blood cell values in GL mice and complement sensitivity of GL red blood cells. / (A) Complement sensitivity of GL red blood cells. Red blood cells from control mice (no. = 3, stippled lines), G+/−L+ mice (no. = 3, bold lines), and mice with blood cells that completely lack GPI-linked proteins (no. = 3, gray lines) were exposed to serial dilutions of acidified human serum. The insert shows one representative example of CD24 expression on red cells from each group of mice analyzed. (B) Hemoglobin levels (Hb) and red blood cell (RBC), platelet (Plt), and reticulocyte (Rtc) counts were obtained from control (empty bars), G+/−L+/− (gray bars), and G+/−L+(/+) (black bars) mice at the age of 4 months. * indicates a statistical significant difference compared with age-matched control mice (P < .05).

Red blood cell values in GL mice and complement sensitivity of GL red blood cells.

(A) Complement sensitivity of GL red blood cells. Red blood cells from control mice (no. = 3, stippled lines), G+/−L+ mice (no. = 3, bold lines), and mice with blood cells that completely lack GPI-linked proteins (no. = 3, gray lines) were exposed to serial dilutions of acidified human serum. The insert shows one representative example of CD24 expression on red cells from each group of mice analyzed. (B) Hemoglobin levels (Hb) and red blood cell (RBC), platelet (Plt), and reticulocyte (Rtc) counts were obtained from control (empty bars), G+/−L+/− (gray bars), and G+/−L+(/+) (black bars) mice at the age of 4 months. * indicates a statistical significant difference compared with age-matched control mice (P < .05).

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