Fig. 4.
![Fig. 4. Assessment of memory type CD8+ T cells in vaccinated mice. / After vaccination, the number of CD8+ T cells expressing activated–memory phenotype (CD44hi CD122+) were estimated by flow cytometry. On day 21, cells expressing these phenotypes increased in IL-10–treated mice (groups 3 and 4) (left), and the absolute number in spleen increased until day 28 (right). (On day 21, group 3 vs group 1, [P < .05]; group 3 vs group 2 [P < .01]; group 3 vs group 4 [P > .05]). The absolute number of such T cells in spleen was thus calculated as (percentage × spleen cell number). Mean values are shown for 3 mice evaluated at each time point.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/98/7/10.1182_blood.v98.7.2143/5/h81911575004.jpeg?Expires=1735556033&Signature=vp8KbYxHdUv96u3zZtdL6fXTmkrdvFWE7yN6jiIMoZWeDelkHFNhUNYE6~YgiC-fizRbjF7VkppzhmAddxX-F6esNA9cekntIm6X7TG9bGgB7Ab5Qsh4M-tscelutX4HDiBR6-JL4L9qRRcKKX~iN8O~nH2M1R-cA0AeUciboUZfXN6Yhh0qCM40w6xG8F5AThO75N~yK7Wx~ay0-qEd1A85M1e-VdoNPokQ0TAzCCdMRIGywrE3xj4zAy92c4qWnMpf~GYBNW0rvFw6w3XtjWCtznTf0tdz-1IGM~te2wkfBDdcgZ1BeTUfmpnRX3MNWz-wTb1~h6fwWJkQUKEzYg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Assessment of memory type CD8+ T cells in vaccinated mice.
After vaccination, the number of CD8+ T cells expressing activated–memory phenotype (CD44hi CD122+) were estimated by flow cytometry. On day 21, cells expressing these phenotypes increased in IL-10–treated mice (groups 3 and 4) (left), and the absolute number in spleen increased until day 28 (right). (On day 21, group 3 vs group 1, [P < .05]; group 3 vs group 2 [P < .01]; group 3 vs group 4 [P > .05]). The absolute number of such T cells in spleen was thus calculated as (percentage × spleen cell number). Mean values are shown for 3 mice evaluated at each time point.
