Surface expression of DIL receptors analyzed in uninfected and HHV-7–infected SupT1 cells by immunofluorescence staining revealed by flow cytometry.

Representative analyses of surface TRAIL receptors (A) and of CD95, TNF-R1, and TNF-R2 (B) performed at 8 days after infection are shown. Uninfected cultures, unshadowed histograms. HHV-7–infected cultures, shadowed histograms. In panel A, the shift of the shadowed histograms along the x-axis illustrates the progressive decrease in the number of TRAIL-R1–expressing cells in HHV-7–infected cultures. In panels A and B, the negative control is represented by uninfected (unshadowed histograms) and HHV-7–infected (shadowed histograms) cultures stained with an irrelevant (Irr) isotype control Ab (Irr Ab). Data shown are from a single experiment representative of 6 independent experiments with similar results.