Analysis of CD55 and CD59 expression and function in B-CLL/PLL.

(A) PBMCs from 33 patients with B-CLL (closed circles) and 4 patients with PLL (closed squares) as well as 4 healthy volunteers (open circles) were double stained with anti–CD20-PE and anti–CD55-FITC, anti–CD59-FITC, or anti–CD46-FITC antibodies and analyzed on the FACS. (B) The CD55 MFI was plotted against the percentage relative lysis for the same patients. (C) The CD59 MFI was plotted against the relative lysis. The results of the statistical analysis are shown in each plot.