Fig. 4.
Aggregation induced by 4N1-1 is strongly reduced in mice deficient in FcR γ chain and SLP-76.
Washed platelets (1 × 108/mL) from WT mice and mice deficient in FcR γ chain and SLP-76 were stimulated with 25 μM 4N1-1, 10 μg/mL collagen, or 0.1 U/mL thrombin. Aggregation was monitored by light transmission. Arrows indicate addition of agonist. Results are representative of experiments using 2 mice for each genotype.
