American Society of Hematology

Fig. 4.

$Fig. 4. Comparison between killer DCs and killer DC-DC hybrids. / (A) The killer DC clone (XS106-7–CD95L) and the killer DC-DC hybrid clone (clone 8) were γ-irradiated and then added to the 2-way MLR in which unfractionated spleen cells isolated from A/J and BALB/c mice were cocultured in the absence of γ-irradiation. (B,C) The same clones were added to the one-way MLR in which responder T cells isolated from the indicated strain were cocultured with splenic DCs purified from the indicated allogeneic strain. All data in this figure are representative of 2 independent experiments, showing the means ± SD (n = 3) of 3H-thymidine uptake. (*P < .05, **P < .01; brackets indicate groups being compared.)$

Comparison between killer DCs and killer DC-DC hybrids.

(A) The killer DC clone (XS106-7–CD95L) and the killer DC-DC hybrid clone (clone 8) were γ-irradiated and then added to the 2-way MLR in which unfractionated spleen cells isolated from A/J and BALB/c mice were cocultured in the absence of γ-irradiation. (B,C) The same clones were added to the one-way MLR in which responder T cells isolated from the indicated strain were cocultured with splenic DCs purified from the indicated allogeneic strain. All data in this figure are representative of 2 independent experiments, showing the means ± SD (n = 3) of ³H-thymidine uptake. (*P < .05, **P < .01; brackets indicate groups being compared.)

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