Fig. 4.
Antileukemia CTL lines are CD8+ class 1 restricted.
After 3 (patient 3 and patient 4) or 4 (patient 1 and patient 2) in vitro stimulations, CTL lines, obtained from PBMCs of BMT recipients (PBMC rec) and from bone marrow cells (BM don) or PBMCs (PBMC don) of BMT donors, were tested for CTL activity, at an E/T ratio of 10:1, against LB target cells in the presence of media only (▨), anti-HLA class 1 (░), anti-HLA class 2 (■), anti-CD8 (▧), and anti-CD4 (▪) mAbs.