Effect of inhibitors on the intracellular fate of His-M195FANCF.

Chloroquine (CHL) or brefeldin A (BFA) was added as indicated. Values represent the ratios (expressed as percentages) of FITC-positive nuclei that have taken up His-M195FANCF relative to the total number of nuclei as assessed by Hoechst staining. For clarity, the controls are assigned a ratio of 1 (or 100%). The mean of 3 independent measurements and standard errors are shown.