Chromosomal imbalances and genomic loss of 8p in MCL.

(A) Summary of chromosomal imbalances detected by CGH in patients with leukemic MCL. Cases 1 to 19 are as presented in Table 1. Red lines on the left of the ideogram indicate loss of chromosomal material, whereas the green lines to the right indicate gain of chromosomal material. Green squares represent high-level DNA amplification. (B) Schematic representation of chromosome 8 genomic abnormalities in patients with MCL and in cell lines with t(11;14)(q13;q32).