Fig. 7.
Normal-phase HPLC profiles of human serum EPO and rhEPO.
Sugar profiling of 2-AB–labeled oligosaccharides from human serum EPO and rhEPO based on the method Guile et al.39 Panel A: 2-AB glycans from human serum EPO isolated from a serum sample taken in 1999 from a patient with aplastic anemia. Panel B: same as panel A, sample taken 1 year later. Panel C: 2-AB glycans from epoetin alfa. Panel D: 2-AB glycans from epoetin beta.