Fig. 7.
Effect of iTCC on chemotaxis and transendothelial migration of PMNs.
Various stimuli, including iTCC (5 nM), IL-8 (10−8 M), or C5a (5 × 10−8 M) were added to the lower compartment of transwells, and PMNs were allowed to migrate from the upper chamber through filters coated with gelatin to test for PMN chemotaxis (░) or with first-passage HUVECs to test for PMN transmigration (▪). The percentage of migrated PMNs was determined after 30 minutes. Values are means ± SD of triplicate determinations of 5 experiments. *P < .01 versus control.
