Effects of

Dll4 overexpression on PB counts and colony formation. PB WBC (panel A) and lymphocyte (panel B) counts from control and Dll4-overexpressing animals, respectively. Data were pooled from 2 transplantation experiments. Twenty mice in each group received transplants. Results are mean ± SEM. WBC and lymphocyte counts in the last 3 data points show large error bars, reflecting that 2 of 20, 6 of 18, and 5 of 15Dll4-overexpressing mice had elevated WBC and lymphocyte counts. The effect of Dll4 overexpression on BM (panel C) and spleen (panel D) colony formation is shown. Mice were analyzed at 4 weeks after BMT. Results are mean ± SEM (n = 5).