Fig. 4.
Fig. 4. BclXL/XS expression, but not Bax or p53 expression, is modified by As2O3 in HTLV-1–transformed and –immortalized cell lines. / Sixty micrograms total protein from C8166 cells was resolved on 10% to 20% Tris-glycine, transferred to PVDF membranes, and probed with specific antibodies for (A) Bax, (B) Bcl-XL/XS, (C) and p53. Results are representative of at least 2 independent experiments using different HTLV-1–infected cells. Comparable protein loading was verified using an antibody specific for the housekeeping gene product β-tubulin (D). Lane 1, control treatment; lane 2, IFN-α; lane 3, As2O3; lane 4, As2O3 + IFN-α.

BclXL/XS expression, but not Bax or p53 expression, is modified by As2O3 in HTLV-1–transformed and –immortalized cell lines.

Sixty micrograms total protein from C8166 cells was resolved on 10% to 20% Tris-glycine, transferred to PVDF membranes, and probed with specific antibodies for (A) Bax, (B) Bcl-XL/XS, (C) and p53. Results are representative of at least 2 independent experiments using different HTLV-1–infected cells. Comparable protein loading was verified using an antibody specific for the housekeeping gene product β-tubulin (D). Lane 1, control treatment; lane 2, IFN-α; lane 3, As2O3; lane 4, As2O3 + IFN-α.

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