Fig. 7.
Caspase-3–dependent cleavage of Bcl-2 promotes release of cytochrome
c from the mitochondria. HUT-102 cells were treated with (A) control buffer, IFN-α (data not shown), As2O3 (data not shown), or (B) with As2O3 + IFN-α for 60 hours. They were stained with a specific cytochrome c antibody and were analyzed by confocal microscopy. Magnification × 63.